Effectiveness of a noninvasive digital infrared thermal
imaging system in the detection of breast cancer.
Arora N, Martins D, Ruggerio D, Tousimis E, Swistel AJ, Osborne MP, Simmons
RM.
Department of Surgery, New York Presbyterian Hospital-Cornell, New York, NY, USA.

BACKGROUND: Digital infrared thermal imaging (DITI) has resurfaced in this era of
modernized computer technology. Its role in the detection of breast cancer is evaluated.

METHODS: In this prospective clinical trial, 92 patients for whom a breast biopsy was
recommended based on prior mammogram or ultrasound underwent DITI. Three scores
were generated: an overall risk score in the screening mode, a clinical score based on
patient information, and a third assessment by artificial neural network. 

RESULTS: Sixty of 94 biopsies were malignant and 34 were benign. DITI identified 58 of 60
malignancies, with 97% sensitivity, 44% specificity, and 82% negative predictive value
depending on the mode used. Compared to an overall risk score of 0, a score of 3 or
greater was significantly more likely to be associated with malignancy (30% vs 90%, P <
.03). 

CONCLUSION: DITI is a valuable adjunct to mammography and ultrasound,
especially in women with dense breast parenchyma.