Wednesday, June 17, 2015

Am J Surg. 2008 Oct;196(4):523-6. Links

Effectiveness of a noninvasive digital infrared thermal imaging system in the detection of breast cancer.

Arora N, Martins D, Ruggerio D, Tousimis E, Swistel AJ, Osborne MP, Simmons
RM. Department of Surgery, New York Presbyterian Hospital-Cornell, New York, NY, USA.

BACKGROUND: Medical infrared thermal imaging (MITI) has resurfaced in this era of
modernized computer technology. Its role in the detection of breast cancer is evaluated.

METHODS: In this prospective clinical trial, 92 patients for whom a breast biopsy was
recommended based on prior mammogram or ultrasound underwent MITI. Three scores
were generated: an overall risk score in the screening mode, a clinical score based on
patient information, and a third assessment by artificial neural network.

RESULTS: Sixty of 94 biopsies were malignant and 34 were benign. MITI identified 58 of 60
malignancies, with 97% sensitivity, 44% specificity, and 82% negative predictive value
depending on the mode used. Compared to an overall risk score of 0, a score of 3 or greater was significantly more likely to be associated with malignancy (30% vs 90%, P <.03).

CONCLUSION: MITI is a valuable adjunct to mammography and ultrasound,
especially in women with dense breast parenchyma.

Wednesday, June 10, 2015

Evaluation of digital infra-red thermal imaging as an adjunctive screening method for breast carcinoma: A pilot study

Int J Surg. 2014 Dec;12(12):1439-43. doi: 10.1016/j.ijsu.2014.10.010. Epub 2014 Nov 7.

Evaluation of digital infra-red thermal imaging as an adjunctive screening method for breast carcinoma: A pilot study. 

Rassiwala M1, Mathur P2, Mathur R3, Farid K3, Shukla S3, Gupta PK4, Jain B4. Author information

Abstract BACKGROUND: Early screening plays a pivotal role in management of breast cancer. Given the socio-economic situation in India, there is a strong felt need for a screening tool which reaches the masses rather than waiting for the masses to reach tertiary centers to be screened. Medical infra-red thermal imaging (MITI) or breast thermography as a screening test offers this possibility and needs to be carefully assessed in Indian scenario.

METHODS: The study involved 1008 female patients of age 20-60 years that had not been diagnosed of cancer of breast earlier. All the subjects in this population were screened for both the breasts using MITI. Based on the measured temperature gradients (ΔT) in thermograms, the subjects were classified in one of the three groups, normal (ΔT ≤ 2.5), abnormal (ΔT > 2.5, <3) and potentially having breast cancer (ΔT ≥ 3). All those having (ΔT > 2.5) underwent triple assessment that consisted of clinical examination, radiological and histopathological examination. Those with normal thermograms were subjected to only clinical examination.

RESULTS: Forty nine female breasts had thermograms with temperature gradients exceeding 2.5 and were subjected to triple assessment. Forty one of these which had ΔT ≥ 3 were proven to be having cancer of breast and were offered suitable treatment. Eight thermograms had temperature gradients exceeding 2.5 but less than 3. Most of these were lactating mothers or had fibrocystic breast diseases. As a screening modality, MITI showed sensitivity of 97.6%, specificity of 99.17%, positive predictive value 83.67% and negative predictive value 99.89%.

CONCLUSION: Based on the results of this study involving 1008 subjects for screening of breast cancer, thermography turns out to be a very useful tool for screening. Because it is non-contact, pain-free, radiation free and comparatively portable it can be used in as a proactive technique for detection of breast carcinoma.

Wednesday, June 3, 2015

Neonatal non-contact respiratory monitoring based on real-time infrared thermography.



Neonatal non-contact respiratory monitoring based on real-time infrared thermography.

Source
Philips Chair for Medical Information Technology, RWTH Aachen University, Pauwelsstr, 20, 52074 Aachen, Germany. abbas@hia.rwth-aachen.de

Abstract

BACKGROUND:
Monitoring of vital parameters is an important topic in neonatal daily care. Progress in computational intelligence and medical sensors has facilitated the development of smart bedside monitors that can integrate multiple parameters into a single monitoring system. This paper describes non-contact monitoring of neonatal vital signals based on infrared thermography as a new biomedical engineering application. One signal of clinical interest is the spontaneous respiration rate of the neonate. It will be shown that the respiration rate of neonates can be monitored based on analysis of the anterior naris (nostrils) temperature profile associated with the inspiration and expiration phases successively.

OBJECTIVE:
The aim of this study is to develop and investigate a new non-contact respiration monitoring modality for neonatal intensive care unit (NICU) using infrared thermography imaging. This development includes subsequent image processing (region of interest (ROI) detection) and optimization. Moreover, it includes further optimization of this non-contact respiration monitoring to be considered as physiological measurement inside NICU wards.

RESULTS:
Continuous wavelet transformation based on Debauches wavelet function was applied to detect the breathing signal within an image stream. Respiration was successfully monitored based on a 0.3°C to 0.5°C temperature difference between the inspiration and expiration phases.

CONCLUSIONS:
Although this method has been applied to adults before, this is the first time it was used in a newborn infant population inside the neonatal intensive care unit (NICU). The promising results suggest to include this technology into advanced NICU monitors.